Overview of Surgical Site Infections: Comprehensive review

Hayallah, Alaa M; Mohamed, Saifalden M.; Nour, Hossam F.; Hassan, Abdelrahman A.; Zaghlol, Omar A.; Bakr, Muhammad M; G. Khalifa, Mohamed G.; Mamdoh, Hend; Tawfeek, Rania Abdelazeem

doi:10.21608/sjpms.2025.413061.1046

Overview of Surgical Site Infections: Comprehensive review

Document Type : Review articles

Authors

¹ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, New Assiut, Egypt

² Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

³ Faculty of Pharmacy, Sphinx University, New Assiut, Egypt

⁴ Department of Microbiology and Immunology, Faculty of Pharmacy, Sphinx University, New Assiut, Egypt

10.21608/sjpms.2025.413061.1046

Abstract

Surgical site infections (SSIs) represent a foremost public health argue, aiding to increased morbidity, mortality, and healthcare budget wide-reaching. They stand as a prominent category within the area of healthcare-associated infections, emerging within a duration of 30 days following a surgical technique at the precise site or anatomical region where the surgery widened. This article presents a comprehensive review of the epidemiology, categorization, Global Incidence, risk factors, microbiological aspects, treatment moods, and prevention approaches for SSIs, based on modern research and evidence-based practice protocols. Vast literature review was overseen, synthesizing existing studies on this title. Inclusion criteria encompassed peer-reviewed articles as well as American and European guidelines focusing on the epidemiology, threat factors, microbiology, treatment, and prevention of SSIs. These findings emphasize the significance of preventive measures, such as appropriate preoperative interventions, strict aseptic techniques, and proper antibiotic prophylaxis, in bring down SSI incidence and improving patient and population outcomes.

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